EDUCATION

EXPERIENCE 

HONORS AND MEMBERSHIPS  

PUBLICATIONS  

1. Zhang, Y.-L., L. Hervio, L. Strandberg and E.L. Madison. 1989. Distinct contributions of residue 192 to the specificity of coagulation and fibrinolytic serine proteases. J Biol. Chem. 274(11):7153-7156.

2. Heymann, J. B., S.D. Zakharov, Y.-L. Zhang, and W. A. Cramer. 1996. Characterization of electrostatic and nonelectrostatic components of protein-membrane binding interactions.  Biochemistry.  70:2774-2783.

3. Zakharov, S.D., 3. B. Heymann, Y.-L. Zhang, and W. A. Cramer. 1996. Membrane binding of the colicin El ion channel: activity requires an electrostatic interaction of intermediate magnitude. Biophysical J. 35(8):27172725.

4. Zhang,Y.-L. and W.A. Cramer. 1993.  Intra-membrane helix-helix interaction as the basis of inhibition of the colicin E1 ion channel by its immunity protein.  J Biol. Chem. 268(14):10176-84. 

5. Zhang, Y.-L. and W. A. Cramer. 1992. Constraints imposed by protease accessibility on the trans membrane and surface topography of the colicin E1 ion channel.  Protein Science.1:1666-1676.

6. Cramer W. A., Y.-L. Zhang,  S. Schendel, A. R. Merrill, H. Y. Song, C. V. Stauffacher and F. S. Cohen. 1992. Dynamic properties of the colicin El ion channel.  FEMS Lett. 105:71-82.

7. Cramer W. A., F. S. Cohen, C. V. Stauffacher, Y.-L. Zhang, A. R. Merrill, H. Y. Song, and P. Elkins. 1992. 

8. Structure-function of the colicin El ion channel: voltage-driven translocation and gating of a tetra- (or hexa-) helix channel. Bacterial Coded Toxins: Bactenocins, Microcins, and Lantibiotics (R. James, C. Lazdunski, F.Pattus, eds.), pp.139-150, Springer-Verlag. Heidelberg.

CONFERENCE PRESENTIONS

1. Zhang, Y.-L., H. Mchaourab, Q.L. Huang, J. Horwitz, W. L. Hubbell. 1996. Interaction of spin-labeled T4 lysozyme with alphA-crystallin. Biophys. J. 70(2), a102.

2. Zakharov, S.D., Y.-L. Zhang, J. B. Heymann, and W. A. Cramer. 1995. Colicin El ion channel binding with membrane: an optimum electrostatic interaction is required for activity. Biophys. J. 68(2), a368.

3. Zhang, Y.-L., J. B. Heymann, and W. A. Cramer. 1994. Characterization of electrostatic interaction in initial binding of colicin El channel domain. Biophys. J. 66(2), a439.

4. Ok, D.C., F.S. Cohen, Y.-L. Zhang, and W. A. Cramer. 1994. Interaction of colicin channels with small voltages is affected by an N-terminal domain. Biophys. J. 66(2), a439.

5. Zhang, Y.-L., and W. A. Cramer. 1993. Intra-membrane helix-helix interaction as the basis of inhibition of the colicin El ion channel by its immunity protein. Biophys. J. 64(2), a345.

6. Cohen F. S., D.C. Ok, Y.-L. Zhang and W. A. Crarmer. 1992. Probing the folding pattern of the colicin E1 channel with tail currents.  Biophys. J. 61(2), a115.

7. Rozenberg, R., Y.-L.Zhang, A.-C., Hector, T. Mirzabekov, M.M. Januszeski, W.L. Hubbell, and W.F. Anderson. 1996.  Membrane distabilization by the cytoplasmic domain of MoMuLV TM.  Cold Spring Harbor Meeting on Retroviruses. May 21- 26, 1996. pp67.

8. Rozenberg, R., A.-C. Hector, T. Mirzabekov, Y.-L. Zhang, W. L. Hubbell, and W.F. Anderson. 1996. Viral entry: a cytoplasmic amphiphilic alpha helix of enlope protein TM functions in virion incorporation and membrane distabilization. Cold Spring Harbor Meeting on Vector targeting strategies for therapeutic gene therapy. March 14-16, 1996. pp67.

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