La Jolla Bioengineering Institute

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Nathaniel G. dela Paz, Ph.D.


Assistant Professor
La Jolla Bioengineering Institute
La Jolla, CA



  • University of California, San Diego, La Jolla, CA Ph.D. 2005 Molecular Pathology
  • University of California, Berkeley, Berkeley, CA B.A. 1996 Molecular and Cell Biology (Genetics Emphasis)

  • 2012-Present   Assistant Professor, La Jolla Bioengineering Institute, La Jolla/San Diego, CA
  • 2010-2012   Research Scientist, La Jolla Bioengineering Institute, La Jolla/San Diego, CA
  • 2007-2012   Postdoctoral Fellow, Schepens Eye Research Institute/Harvard Medical School, Boston, MA
  • 2005-2007   Postdoctoral Fellow, Children’s Hospital Boston/Harvard Medical School, Boston, MA
  • 1996-1999   Research Technician, The Scripps Research Institute, La Jolla, CA

Honors and Memberships
  • 2015-Present   Member, American Society for Biochemistry and Molecular Biology
  • 2012-Present   Investigator, NHLBI Diversity Research Supplement
  • 2008-2009   Member, North American Vascular Biology Organization
  • 2008-2009   Trainee, Molecular Bases of eye diseases Training Program, Schepens Eye Research Institute/Harvard Medical School
  • 2005-2008   Trainee, Pathobiology of the Developing Cardiovascular System, Cardiac Registry, Children's Hospital Boston
  • 2003-2005   Principal Investigator, Ruth L. Kirschstein NRSA Predoctoral Fellowship Program, NHLBI, National Institutes of Health
  • 2004   ASBMB Graduate Minority Travel Award, FASEB MARC Program
  • 2002   ASBMB Graduate Minority Travel Award, FASEB MARC Program
  • 2001   ASBMB Graduate Minority Travel Award, FASEB MARC Program
  • 1996   Intern, Summer Undergraduate Research Fellows Program, The Scripps Research Institute

Selected Publications

Heparan sulfates mediate the interaction between Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) and the Gaq/11 subunits of heterotrimeric G proteins.

dela Paz NG, Melchior B, Shayo FY, Frangos JA

J Biol Chem. 2014 Mar 14;289(11):7413-24.


The role of shear-induced Transforming Growth Factor-? signaling in the endothelium

Walshe TE, dela Paz NG, D’Amore PA

Arterioscler Thromb Vasc Biol. 2013 Nov;33(11):2608-17.


Early VEGFR2 activation in response to flow is VEGF-dependent and mediated by MMP activity

dela Paz NG, Melchior B, Frangos JA

Biochem Biophys Res Commun. 2013 May 10;434(3):641-6.


Role of shear-stress-induced VEGF expression in endothelial cell survival

dela Paz NG, Walshe TE, Leach LL, Saint-Geniez M, D'Amore PA

J Cell Sci. 2012 Feb 15;125(Pt 4):831-43

Arterial versus venous endothelial cells

dela Paz NG, D'Amore PA

Cell Tissue Res. 2009 Jan;335(1):5-16


Regulation of NF-kappaB-dependent gene expression by the POU domain transcription factor Oct-1

dela Paz NG, Simeonidis S, Leo C, Rose DW, Collins T

J Biol Chem. 2007 Mar 16;282(11):8424-34


Autoimmune alterations induced by the New Zealand Black Lbw2 locus in BWF1 mice

Haraldsson MK, dela Paz NG, Kuan JG, Gilkeson GS, Theofilopoulos AN, Kono DH

J Immunol. 2005 Apr 15;174(8):5065-73

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