The heart of the Institute’s research is to determine how mechanical forces play a role in the normal physiology and pathology of blood vessels, bone, and muscle. The Institute uses an interdisciplinary approach that involves fluid and solid mechanics and molecular and cell biology to answer this fundamental question. The work on mechanochemical signal transduction in endothelial and bone cells has provided insight of direct clinical relevance.
Most of our current research efforts are supported by multi-year grants awarded through the National Institutes of Health NIH. Here is a list of them.
- Interstitial Fluid Flow in Bone Remodeling
- Mechanosensitivity of Cell Membranes: Role of Lipid-Protein Interactions
- Multiplexed Analysis of Serum Antibodies to Influenza Virus
- Nitric Oxide Protects Against Microcirculatory Complications of Malaria
- Nitric Oxide Restoration & Heme Detoxification as Adjunctive Therapies for Cerebr
- Raman Flow Cytometry for Diagnostics and Drug Discovery
- Shear Stress Activation of Endothelial Membrane Function
- The Role of Dipole Potential in Mechanosensing